Avtor/Urednik     Cilenšek, Ines; Mankoč Ramuš, Sara; Globočnik Petrovič, Mojca; Petrovič, Danijel
Naslov     The glutathione reductase (GSR) polymorphisms (rs1002149 and rs8191009) and diabetic retinopathy in Slovenian subjects with type 2 diabetes mellitus
Tip     članek
Vol. in št.     Letnik 1, št. 5
Leto izdaje     2016
Obseg     str. 1-5
Jezik     eng
Abstrakt     The present work was carried out to evaluate a possible association between two polymorphisms (rs1002149 and rs8191009) in the GSR gene coding for antioxidant enzyme, and DR in 804 unrelated Slovene subjects (Caucasians) with T2DM. No differences were observed in genotype distribution between the two groups for either polymorphism in the GSR gene. No significant differences in serum 8-OHdG levels among subjects with DR stratified according to three possible genotypes were observed. In our study, we did not demonstrate an association between either rs1002149 or rs8191009 and DR in subjects with T2DM.
Proste vsebinske oznake     diabetes type 2
diabetic retinopathy
oxidative stress
diabetes tip 2
diabetična retinopatija
oksidativni stres