Avtor/Urednik     López, Fernando; Williams, Michelle D.; Cardesa, Antonio; Hunt, Jennifer L.; Strojan, Primož; Rinaldo, Alessandra; Nixon, Iain J.; Rodrigo, Juan Pablo; Saba, Nabil F.; Mendenhall, William M.; Quer, Miquel
Naslov     How phenotype guides management of non-conventional squamous cell carcinomas of the larynx
Tip     članek
Vol. in št.     Letnik 274, št. 7
Leto izdaje     2017
Obseg     str. 2709-2726
ISSN     0937-4477 - European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Jezik     eng
Abstrakt     Although the majority of laryngeal malignancies are the conventional squamous cell carcinomas (SCC), a wide variety of malignant epithelial tumors can affect the larynx. Current treatment guidelines are designed to guide clinicians in management of conventional laryngeal SCC. Less is known about the biological behavior and responsiveness to therapy and overall outcomes of other malignant epithelial lesions. Because a spectrum of disease biology is represented by these rare phenotypes, an understanding of the basic biology can help direct management to optimize clinical outcome in this group of patients. This review provides a critical analysis of literature relating to the diagnosis, management, and outcome of patients with non-conventional squamous malignant epithelial neoplasms of the larynx. Particular attention is paid to features which are at variance with the conventional SCC and how these impact on management of these rare tumors.
Proste vsebinske oznake     verukozni ploščatocelični rak
papilarni ploščatocelični rak
histologija
rak grla
verrucous squamous cell carcinoma
papillary squamous cell carcinoma
histology
laryngeal cancer