Avtor/Urednik		Vardjan, Nina
Naslov		Mechanism and drug targets for reducing cell edema (neuroprotection) and cytoplasmic excitability in astrocytes in normal and pathological states
Tip		monografija
Kraj izdaje		Alexandria
Založnik		United States Patent and Trademark Office
Leto izdaje		2018
Obseg		str. 17 str.
Jezik		eng
Abstrakt		The present invention pertains to a method for screening a compound useful in reducing astroglial edema, said method comprising: (i) providing a compound; (ii) bringing said compound in contact with an astrocyte; and (iii) determining the cAMP level in said astrocyte contacted with said compound; wherein said compound is identified as a compound useful in reducing astroglial edema, if the cAMP level in the astrocyte increases after contact. The present invention further pertains to an agent elevating the cAMP level in astrocytes for use in reducing astroglial edema.
Proste vsebinske oznake		astrocyte astroglial edema agent elevating the cAMP level astrociti astroglialni edem sredstvo, ki dviguje raven cAMP