Avtor/Urednik		Tršinar, Bojan; Kreft, Samo
Naslov		Effect of saw palmetto extract on erectile dysfunction and libido in patients with lower urinary tract symptoms because of benign prostatic obstruction
Tip		članek
Vol. in št.		Letnik 2, št. 1
Leto izdaje		2019
Obseg		str. 1-6
ISSN		2214-7861
Jezik		eng
Abstrakt		Background: Herbal medicinal products containing extracts of saw palmetto berries (Serenoa repens) are used for treatment of Lower Urinary Tract Symptoms (LUTS) because of Benign Prostatic Obstruction (BPO). Improvement of sexual dysfunctions was also shown. Methods: Here we performed a multicentric open label clinical study on 84 men to confirm its effects on LUTS/BPO on Slovenian population and this is only the second study investigating the effect on sexual dysfunctions. Results: In 6 months of treatment the International prostate symptom score (IPSS) improved from 12.7 to 9.2 (p = 7.0%10-12) and the quality of life score improved from 2.4 to 1.7 (p = 9.2%10-4). Prostate-Specific Antigen (PSA) levels did not change. The proportion of patients with unsatisfactory libido reduced from 26.5 % to 13.2 % (p=0.036) during the therapy and a non-significant trend of reduction of erectile dysfunction was observed. Conclusion: Our results are in agreement with the previous research on the efficacy of saw palmetto, but regarding the libido and erectile dysfunction, further controlled studies are needed.
Deskriptorji		Erektilna disfunkcija
Proste vsebinske oznake		berries erectile dysfunction libido Saw Palmetto (Serenoa Repens) Slovenian population žagastolistna palma