Avtor/Urednik		Grmek-Košnik, Irena; Eberl-Gregorič, Edita; Ribič, Helena; Ribnikar, Monika; Orožen, Kristina; Lavtižar, Jana; Dolenc, Matej; Poklukar, Janez; Sočan, Maja
Naslov		Izbruh gripe v Splošni bolnišnici Jesenice v letu 2017 pri bolnikih in zdravstvenih delavcih
Prevedeni naslov		Influenza outbreak in patients and healthcare professionals of the Jesenice General Hospital in 2017
Tip		članek
Vol. in št.		Letnik 88, št. 11/12
Leto izdaje		2019
Obseg		str. 517-528
ISSN		1318-0347 - Zdravniški vestnik : glasilo Slovenskega zdravniškega društva : Slovenian medical journal
Jezik		slv
Abstrakt		Background: Influenza is a seasonal viral respiratory disease that occurs during winter months. It is caused by type A and B influenza viruses. Influenza outbreaks in hospitals are particularly unfavourable as the vulnerable population becomes ill. Many complications occur, hospital tre - atment is prolonged and mortality increases. Healthcare professionals (HW) may also become ill and because of their absenteeism problems arise in the organization of work. Methods: We present a retrospective cohort study of an influenza outbreak in a General Hospital Jesenice which occured in a period from 1 January to 16 February 2017. A case definition was as follows: A patient or a healthcare professional (PW) who had signs of influenza-like illness (fever above 37.77 °C with coughing or sore throat) in the absence of other causes of infection and either influenza A or B virus confirmed in the nasopharingeal swab, or in whom an epidemiological link with a confirmed case (hospitalisation in the same room) was established. Patients who developed these symptoms and signs 72 hours or later after admission were classified as nosocomial cases. We asked the affected HP about demographic data, any previous vaccination against influenza, and their subjective assessment of the severity of the disease. Results: Of the approximately 250 exposed people, 117 (46.8%) fell ill. The first cases occurred in the internist department, followed by the surgical and nursing departments. The majority of patients were aged 65 and over. We took nasopharyngeal swabs from 74 patients and employees who complied with the definition of the case in the outbreak. Influenza A (87 %) or B (13 %) was confirmed in 68 (87 %) samples. The remaining 49 cases that were not laboratory-confirmed have met the epidemiological link criteria. In the discharge letters of all 13 deceased patients one of the discharge diagnoses was influenza, while in four it was also listed as the direct cause of death. Six patients died of pneumonia that followed the flu. Fortyfive patients received oseltamivir, 61 hospitalized patients, and HW took oseltamivir as chemoprophylaxis. The outbreak of influenza had an adverse effect on the work plan of the surgical department - due to the outbreak, the number of elective surgeries decreased and a part of the surgical beds were allocated to the overwhelmed internist department. Conclusion: At an early stage of an outbreak in a hospital, a high degree of compliance with preventive measures is required. Patients' comorbidities and poor general condition contribute to more severe clinical presentation of influenza. Problems in ensuring isolation, non-compliance with the recommendations for personal hygiene of patients, non-vaccination against influenza and poor response of the immune system of elderly patients to vaccination contribute to outbreaks.
Proste vsebinske oznake		gripa influenca izbruh flu influenza outbreak