Avtor/Urednik		Pavan-Jukić, Doroteja; Starc, Andrej; Štubljar, David; Jukić, Tomislav
Naslov		Obesity with high body mass index does not influence sperm retrieval in males with azoospermia
Tip		članek
Vol. in št.		, št. Vol. 26
Leto izdaje		2020
Obseg		str. 1-6
ISSN		1643-3750 - Medical science monitor : international medical journal of experimental and clinical research
Jezik		eng
Abstrakt		Background: The aim of this study was to evaluate the influence of male body mass index (BMI) on the retrieval of sperm from azoospermic patients who were undergoing testicular sperm extraction (TESE). Material/Methods: The study included retrospective data of male patients suffering from non-obstructive azoospermia (NOA). Age, BMI, testicular volumes, the serum concentration of the follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and prolactin were investigated and collected. Results: A total of 75 azoospermic males were evaluated between 2014 and 2019, including 35 patients (46.7%) with positive sperm retrieval. The majority of patients (57.3%) had normal BMI (between 20 kg/m2 and 25 kg/m2) or first degree obesity (from 25 kg/m2 to 30 kg/m2). No statistically significant correlation between BMI and positive sperm retrieval or hormone levels (LH, FSH, SHBG, prolactin) were found. However, lower serum testosterone levels were observed in patients with higher BMI (P=0.035). Receiver operating characteristic curve analysis showed that none of the hormones could potentially predict the positive outcome of TESE. Conclusions: The hormonal levels or patient's BMI could not predict positive sperm retrieval outcome, however a negative correlation between serum testosterone and BMI levels was calculated implicating influence on fertility.
Proste vsebinske oznake		azoospermia body mass index obesity sperm retrieval testosterone