Avtor/Urednik		Goswami, Nandu; Taucher, Alexander Andreas; Brix, Bianca; Roessler, Andreas; Koestenberger, Martin; Reibnegger, Gilbert; Cvirn, Gerhard
Naslov		Coagulation changes during central hypovolemia across seasons
Tip		članek
Vol. in št.		Letnik 9, št. 11
Leto izdaje		2020
Obseg		str. 1-12
ISSN		2077-0383 - Journal of clinical medicine
Jezik		eng
Abstrakt		Lower body negative pressure (LBNP) application simulates hemorrhage. We investigated how seasons affect coagulation values at rest and during LBNP. Healthy participants were tested in cold (November-April) and warm (May-October) months. Following a 30-min supine period, LBNP was started at %10 mmHg and increased by -10 mmHg every five minutes until a maximum of - 40 mmHg. Recovery was for 10 min. Blood was collected at baseline, end of LBNP, and end of recovery. Hemostatic profiling included standard coagulation tests, calibrated automated thrombogram, thrombelastometry, impedance aggregometry, and thrombin formation markers.
Proste vsebinske oznake		seasons coagulation LBNP thrombelastometry thrombin generation trhombogram