Avtor/Urednik     Večerić-Haler, Željka; Kojc, Nika; Sever, Matjaž; Zver, Samo; Švajger, Urban; Poženel, Primož; Pretnar-Hartman, Katrina; Urdih, Tereza; Mlinšek, Gregor; Oblak, Manca; Aleš, Andreja; Ihan, Alojz; Buturović-Ponikvar, Jadranka; Halloran, Philip F.; Arnol, Miha
Naslov     Capillary leak syndrome with kidney transplant failure following autologous mesenchymal stem cell therapy
Tip     članek
Vol. in št.     , št. Vol. 8
Leto izdaje     2021
Obseg     str. 1-7
ISSN     2296-858X - Frontiers in Medicine (Online)
Jezik     eng
Abstrakt     Mesenchymal stem cells (MSCs) have attracted great interest in the field of kidney transplantation due to their immunomodulatory and reparative properties. In registered clinical trials, MSCs have been used before, at the time of, or early after transplantation and have been reported to be well-tolerated with no serious safety concerns. No results are available on the use of MSCs in the late post-transplant period. Here, we present a case report of a severe systemic complication mimicking capillary leak syndrome with ultimate kidney transplant failure after autologous transplantation of MSCs used as rescue treatment of late antibody-mediated kidney allograft rejection.
Proste vsebinske oznake     mesenchymal stem cell
kidney transplant
kidney graft failure
mezenhimske izvorne celice
presaditev ledvice
odpoved ledvičnega presadka