Avtor/Urednik		Patrinos, George P.; Andritsou, Asimina; Chalikiopoulou, Konstantina; Mendrinou, Effrosyni; Tsermpini, Evangelia Erini
Naslov		Pharmacogenomics in clinical care
Tip		članek
Vir		In: Applied genomics and public health London, United Kingdom San Diego, CA : Elsevier/Academic Press
Leto izdaje		2020
Obseg		str. 111-130
Jezik		eng
Abstrakt		Pharmacogenomics refers to the genetic basis of the interindividual differences in drug response, in terms of efficacy and toxicity. Pharmacogenomics aims to redefine disease management and patient stratification, with direct impact not only on the quality of life of the patients but also on the reduction of the overall cost of health-care expenditure. The latter has important implications in modern clinical practice as well as public health. This chapter aims to summarize our current knowledge pertaining to the applications of pharmacogenomics in clinical care, in particular the most important medical specialties, namely, cardiology, oncology, and psychiatry, and also addresses important aspects of pharmacogenomics in relation to public health.
Proste vsebinske oznake		farmakogenomika neželeni učinki zdravila javno zdravje pharmacogenomics adverse drug reactions public health