Avtor/Urednik     Kokalj, Anja; Rijavec, Nikolina; Tavčar, Rok
Naslov     Delirium with anticholinergic symptoms after a combination of paliperidone and olanzapine pamoate in a patient known to smoke cannabis
Tip     članek
Vol. in št.     , št. Vol. 2016
Leto izdaje     2016
Obseg     str. 1-3
ISSN     1757-790X - BMJ case reports
Jezik     eng
Abstrakt     We report a case of delirium with anticholinergic symptoms in a 19-year-old female patient with schizophrenia. On the day the symptoms emerged, the patient received olanzapine long-acting injection and a higher dose of paliperidone. We observed symptoms ranging from confusion to delirium as well as some anticholinergic symptoms. The delirium lasted 24 hours and was managed by intravenous fluid substitution and oral benzodiazepines. Olanzapine pamoate, paliperidone and cannabis are central nervous system (CNS) depressants, and their combination can increase the risks of CNS depression. In this case report, we review the symptoms of delirium in a case of antipsychotic overdose and provide general guidelines for managing these symptoms. We also review possible complications in combined use of cannabis, olanzapine and paliperidone.
Proste vsebinske oznake     anticholinergic symptoms
delirium
cannabis
antiholinergični simptomi
delirij
konoplja