Avtor/Urednik		Franić, Damir; Fistonić, Ivan; Franic Ivanisevic, Maja; Perdija, Željko; Križmarić, Miljenko
Naslov		Pixel CO2 laser for the treatment of stress urinary incontinence
Tip		članek
Vol. in št.		Letnik 53, št. 4
Leto izdaje		2021
Obseg		str. 514-520
ISSN		1096-9101 - Lasers in surgery and medicine
Jezik		eng
Abstrakt		Background and Objectives: Energy-based treatments have been found to be a promising treatment modality for improving stress urinary incontinence (SUI) symptoms. This prospective two-center study was designed to evaluate the efficacy of fractiona-pixel CO2 laser for the treatment of SUI. Study Design/Materials and Methods: Eighty-five women with SUI symptoms as per the cough stress test and validated International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI-SF), were treated intravaginally with Pixel-CO2 laser. Two treatment sessions were performed with a 1-month interval. Safety and treatment tolerance were assessed by the visual analog scale (VAS) immediately and at 1 week after each laser treatment. Associations of age and body mass index (BMI) with the ICIQ-UI-SF score were statistically assessed by the Jonckheere-Terpstra test. Results: The ICIQ-UI-SF score was 12.0 at baseline, 7.0, after the first treatment, and 3.5 after the second treatment (P = 0.001). For women with BMI (25.0-29.9), the ICIQ-UI-SF score was 9.0 at the baseline, 6.0 after 1 month, and 5.0 at the 6 months follow-up visit (P = 0.04). For women with BMI % 30.0, the ICIQ-UI-SF score was reduced from 14.0 to 8.0 1 month after the baseline and 5.0 at the 6-month follow-up visit (P = 0.001). SUI severity evaluation at baseline showed that 27.1% of women had mild, 24.7% had moderate, 45.9% had severe, and 2.4% had very severe SUI symptoms. SUI severity scores were significantly reduced, with 45.8% of women with no SUI symptoms, 18.8% with mild, 20.8% with moderate, and 14.6% with severe SUI symptoms at the 6-month follow-up. The patient's evaluation of VAS after the first treatment was 1.0-1.5 (0%10) and 0.0 1 week after the second treatment. Conclusion: Fractional-pixel CO2 laser is safe and effective for treating SUI. No adverse event or significant pain was reported during or after the procedure. Its safety and efficacy are clearly demonstrated.
Proste vsebinske oznake		stress urinary incontinence pixel CO2 laser stresna inkotinenca zdravljenje z laserjem CO2 laser točkovni laserji