Avtor/Urednik		Vitas, M; Rozman, D; Komel, R; Kelly, SL
Naslov		Progesterone side-chain cleavage by Paecilomyces lilacinus
Tip		članek
Vir		Phytochemistry
Vol. in št.		Letnik 40, št. 1
Leto izdaje		1995
Obseg		str. 73-6
Jezik		eng
Abstrakt		The filamentous fungus Paecilomyces lilacinus converts progesterone to more polar compounds by a side-chain cleavage reaction. We have investigated the role of cytochrome P-40 in this mono-oxygenase reaction and confirmed the involvement of other cytosolic enzymes. The activity was found to be NADPH-dependent and inducible by pre-exposure of mycelium to progesterone.
Deskriptorji		PAECILOMYCES CYTOCHROME P-450 PROGESTERONE HYDROXYLATION