Avtor/Urednik     Urleb, U; Krbavčič, A; Sollner, M; Kikelj, D; Pečar, S
Naslov     Synthesis of phthalimido-desmuramylpeptide analogues as potential immunomodulating agents
Tip     članek
Vir     Arch Pharm (Weinheim)
Vol. in št.     Letnik 328, št. 2
Leto izdaje     1995
Obseg     str. 113-7
Jezik     eng
Abstrakt     The preparation of immunologically active phthalimido desmuramylpeptide analogues 2e-h, 4c-d, and 7b is described. The N-acetylmuramic acid in the muramyl dipeptide has been replaced by a phthaloylated acyclic moiety such as N-phthaloylated amino acids 1a-c, 2-(2-phthalimidoethoxy)acetic acid 3, or by the carbocyclic rac. trans-2-(2'-phthalimidocyclohexyloxy)acetic acid 6.
Deskriptorji     ADJUVANTS, IMMUNOLOGIC
PEPTIDES
PHTHALIMIDES
ADJUVANTS, IMMUNOLOGIC
CYCLOPHOSPHAMIDE
IMMUNOSUPPRESSIVE AGENTS
MICE
PEPTIDES
PHTHALIMIDES