Avtor/Urednik		Furlan, Ladica; Šmid, Lojze; Strojan, Primož
Naslov		Rezultati zdravljenja bolnikov s karcinomom ustnega žrela, obravnavanih na Otorinolaringološki kliniki in Onkološkem inštitut v Ljubljani v letih od 1980 do 1990
Prevedeni naslov		The results of oropharyngeal carcinoma treatment at the Department of Otorhinolaryngology and Institute of oncology in Ljubljana in the years 1980-1990
Tip		članek
Vir		Med Razgl
Vol. in št.		Letnik 35, št. Suppl 6
Leto izdaje		1996
Obseg		str. 169-72
Jezik		slo
Abstrakt		The objective of the study was a retrospective analysis of the results of combined treatment *surgery pharyngeal carcinoma. Seventy-seven patients with histologically confirmed oropharyneal carcinoma were included in the analysis. There were 66 males (median age 54 years) and 11 females (median age 56 years). Tumor origin was lateral oropharyngeal wall in 37, base of the tongue in 39 and soft palate in 1 patient. Stage of disease was as follows: I - 3, II - 11, III - 23 and IV - 40 patients. Median follow-up was 112 months. Overall survival of trated patients was 19 %, disease-free survival 56 % and disease-specific survival 58 %. In 17 patients a new primary was diagnosed. There was no statistically significant correlation observed between survival and several possible prognostic factors (sex, stage, site of tumor origin, histology).
Izvleček		Namen študije je bila pregledna razčlenitev rezultatov kombinranega zdravljenja (operacija in obsevanje po operaciji) bolnikov s karcinomom ustnega žrela. V študijo smo vključili 77 bolnikov s histološko potrjenim rakom ustnega žrela - 66 moških z povprečno starostjo 54 in 11 žensk z povprečno starostjo 56 let. Pri 37 bolnikih je tumor izviral iz stranske stene ustnega žrela, pri 39 iz korena jezika, pri enem iz mehkega neba. Trije bolniki so bili v prvem, 11 v drugem, 23 v tretjem in 40 v četrtem stadiju bolezni. Povprečen čas opazovanja bolnikov je znašal 112 mesecev. Skupno preživetje bolnikov je bilo 19 % preživetje brez ponovitve bolezni 56 % in specifično preživetje 58 %. Sedemnajst bolnikov je dobilo nov primarni maligni tumor. Preživetje ni bilo statistično značilno povezavo z nobenim izmed analiziranih napovednih dejavnikov (spol, stadij bolezni, mesto izvora tumorja, histološka slika).
Deskriptorji		OROPHARYNGEAL NEOPLASMS SURVIVAL RATE TREATMENT OUTCOME NEOPLASM STAGING