Avtor/Urednik     Picken, RN; Cheng, Y; Strle, F; Picken, MM
Naslov     Patient isolates of Borrelia burgdorferi sensu lato with genotypic and phenotypic similarities to strain 25015
Tip     članek
Vir     J Infect Dis
Vol. in št.     Letnik 174, št. 5
Leto izdaje     1996
Obseg     str. 1112-5
Jezik     eng
Abstrakt     Strain 25015 is an atypical tick isolate that belongs to a distinct genomic group (DN127) within the general taxon Borrelia burgdorferi sensu lato. Similarities between this strain and a white-footed mouse isolate from Illinois, strain CT39, have been reported. In the course of isolating B. burgdorferi sensu lato in culture from Slovenian patients, 9 isolates were identified with the same genetic profiles as strains 25015 and CT39, as evidenced by restriction enzyme MluI digestion patterns of genomic DNA. The aim of the present study was to molecularly characterize all 11 isolates to examine the extent of their genotypic and phenotypic similarity. The results of molecular studies suggest a close relationship between the patient isolates and strains 25015 and CT39. However, CT39 and several patient isolates possessed unique characteristics that reflect their discrete ontogeny.
Deskriptorji     BORRELIA BURGDORFERI
BACTERIAL PROTEINS
GENOTYPE
PEROMYSCUS
PHENOTYPE
PLASMIDS
ELECTROPHORESIS, GEL, PULSED-FIELD
RNA, RIBOSOMAL, 5S