Avtor/Urednik		Žvan, Bojana; Zaletel, Marjan; Pečnik, Borut; Pogačnik, Tomaž
Naslov		Risk factors for stroke in patients with transient ischemic attack
Tip		članek
Vir		J Stroke Cerebrovasc Dis
Vol. in št.		Letnik 6, št. Suppl 1
Leto izdaje		1996
Obseg		str. 123-8
Jezik		eng
Abstrakt		The natural course of transient ischemic attack (TIA) is variable; some patients are at high and others are at low risk of serious vascular events. We tried to identify the sugroup of TIA patients with high risk of ischemic stroke (IS). Therefore, we investigated the correlation of sonographic findings and systemic risk factors with IS and TIA patients. We examined 113 patients with IS, who had history of carotid TIA (mean age, 61.2+-16.7 years) and 142 patients with carotid TIA (mean age, 59.3+-15.2 years). Initial data collection included parameters such as age and gender, as well as a family history of stroke, the presence of diabetes mellitus, arterial hypertension, heart disease, lipid status, cigarette smoking, physical activity, and alcohol consummation. A noninvasive examination was performed by using color-coded duplex sonography (CCDS). No statistically differences in age and gender were found between the groups, neither between the common carotid artery intimal-medial thickness in TIA and IS patients or between the number of plaques. A significant higher proportion of occlusions (P=.032) of internal coratid arteries (ICA) was found in the IS group. Among the subtype of stenosis, the hemodinamically significant (HS) stenosis was found to be higher in the IS group (P=.007). We found a higher proportion of stenosating soft dyshomogenous plaques (P=.043). Among the systemic risk factors, arterial hypertension (P=.039), diabetes mellitus (P=.012), and cigarette smoking (P=.043) were associated with the IS group. In conclusion, HSICA stenosis and occlusion appear to be the risk factors for stroke in TIA patients. The soft dyshomogeneous stenotic plaques are associated with greater risk of ischemic stroke. Among systemic risk factors, arterial hupertension, diabetes mellitus, and cigarette smoking were found to be riks factors for stroke in TIA patients.
Deskriptorji		CEREBRAL ISCHEMIA, TRANSIENT RISK FACTORS CEREBROVASCULAR DISORDERS DIABETES MELLITUS HYPERTENSION SMOKING ALCOHOL DRINKING LIPIDS CORONARY DISEASE CAROTID ARTERIES ULTRASONOGRAPHY, DOPPLER, DUPLEX