Avtor/Urednik		Lešničar, H; Šmid, L; Zakotnik, B
Naslov		Early glottic cancer: the influence of primary therapy on ultimate organ preservation
Tip		članek
Vir		In: Kogelnik HD, editor. Progress in radio-oncology 5. Proceedings of the 5th international meeting on progress in radio-oncology ICRO/OEGRO 5; 1995 May 10-14; Salzburg. Bologna: Monduzzi editore,
Leto izdaje		1995
Obseg		str. 229-34
Jezik		eng
Abstrakt		To achieve better comparison of final treatment results between 44 primarily operated and 219 primarily irradiated patients with early glottic cancer, retrospective identification of patients based on criteria of suitability for voice-sparing operation was made. In patients, found to be suitable for organ preservation surgery 10-years disease specific survival (DSS) of 94% vs. 92% in T1 and 94% vs. 87% in T2 tumors was estimated for primarily operated and irradiated patients reseptively (p=0.1). If the over-all treatment time in primary irradiated patients was shorter than 48 days, final preservation of larynx was achieved in 97% and was identical with the primary surgery group. In patients with T2 tumors unsuitable for voice-sparing operation significantly lower 10-years DSS, namely 71% vs. 65%, for primary surgery and radiotherapy respectively was found. If treated with primary surgery all these patients would have nedeed total laryngectomy, however with primary radiotherapy with over-all treatment time shorter than 48 days, the final preservation of voice succeded in 87% of patients.
Deskriptorji		LARYNGEAL NEOPLASMS GLOTTIS NEOPLASM STAGING LARYNX SURVIVAL ANALYSIS VOICE