Avtor/Urednik		Čižman, Milan; Paragi, Metka; Jovan-Kuhar, Nadja; Gubina, Marija; Oražem, Andreja; Pokorn, Marko; et al, ;
Naslov		Antimicrobial resistance of invasive streptococcus pneumoniae in Slovenia, 1993-1995
Tip		članek
Vir		Scand J Infect Dis
Vol. in št.		Letnik 29
Leto izdaje		1997
Obseg		str. 251-4
Jezik		eng
Abstrakt		The susceptibility of 108 Streptococcus pneumoniae strains isolated from normally sterile body sites during 1993-1995 in Slovenia has been studied. Overall resistance to penicillin, erythromycin, trimethoprim-sulfamethoxazole, cefuroxime, cefaclor and chloramphenicol was 16.6, 0.9, 28.8, 0, 4.5 and 4.6%, respectively. All penicillin-resistant isolates (intermediate resitance) were susceptible to cefotaxime, ceftriaxone and vancomycin. Isolates less suceptible to penicillin were also significantly less sensitive to chloramphenicol, cefaclor and trimethoprim-sulfamethoxazole than penicillin-sensitive strains. Pneumococci isolated in children were significantly (p < 0.05) more resistant to trimethoprim-sulfamethoxazole than those isolated in adults. The study demonstrated moderate resistance rate of S. pneumoniae to penicillin and trimethoprim-sulfamethoxazole and a low-level resistance rate to erythromycin, cefaclor and chloramphenicol. No straightforwad correlation between overall consumption of antibiotics and antimicrobial resistance was found.
Deskriptorji		DRUG RESISTANCE, MICROBIAL PENICILLIN RESISTANCE PNEUMOCOCCAL INFECTIONS STREPTOCOCCUS PNEUMONIAE ANTI-INFECTIVE AGENTS CEPHALOSPORINS CHLORAMPHENICOL DRUG RESISTANCE, MULTIPLE MICROBIAL SENSITIVITY TESTS SEROTYPING SLOVENIA TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION