Avtor/Urednik		Rogl-Butina, Mirjam; Dolenc-Voljč, Mateja; Potočnik, Marko; Bartenjev, Igor
Naslov		Kožne spremembe pri bolnikih, okuženih s HIV
Prevedeni naslov		Skin manifestations in HIV infected patients
Tip		članek
Vir		Med Razgl
Vol. in št.		Letnik 36, št. Suppl
Leto izdaje		1997
Obseg		str. 135-49
Jezik		slo
Abstrakt		Cutaneous and mucosal manifestations develop in most patients infected with HIV They can occur already at the start as an acute HIV illness or later during developed HIV disease and aids. One can divide them into manifestations which are most probably directly related to HIV infection and those whose relationship with HIV has not been clarified yet. A third category includes preexisting or coexisting dermatological conditions whose course and therapeuthic response are altered by HIV infection. Most common manifestations of progressive immunosuppression that accompanies HIV infection are frequent and severe infections, mucocutaneous and/or systemic. They can be caused either by fungi, bacteria or viruses. A connection between HIV infection and incidence of various cutaneous malignancies is evident in some cases and somewhat blurred in others. Among many other mucucutaneous signs and symptoms we mention different pruritic papular and papulopustular eruptions and various drug reactions.
Izvleček		Spremembe na koži in/ali sluznicah se razvijejo skoraj pri vsaki osebi, okuženi s HIV bodisi že ob akutnem HIV-sindromu ali kasneje ob napredovali HIV bolezni in aidsu. V grobem jih razdelimo na spremembe, ki so najverjetneje neposredno povezane s HIV-okužbo in spremembe, katerih odnos s HIV ni popolnoma jasen, se pa statistično pogosteje pojavljajo pri okuženih. Tretjo skupino tvorijo sicer znane in pogoste dermatoze, katerih potek, klinična slika in odgovor na zdravljenje pa se spremenijo po okužbi s HIV. Najpogosteje se ob napredovali imunski pomankljivosti pojavljajo različne okužbe z bodisi le lokalno ali tudi sistemsko prizadetostjo; povzročajo jih lahko glive, bakterije in virusi. Povezava med okužbo s HIV in nekaterimi neoplazmami je zelo očitna, medtem ko je odnos z drugimi še nedorečen. Posebno mesto med kožnimi in sluzničnimi spremembami pri okuženih s HIV imajo različne srbeče papulozne in papulopustulozne dermatoze ter izjemno pogosti preobčutljivostni odgovori na zdravila.
Deskriptorji		HIV INFECTIONS SKIN MANIFESTATIONS SEXUALLY TRANSMITTED DISEASES, VIRAL DERMATOMYCOSES SKIN DISEASES, BACTERIAL SKIN DISEASES, VIRAL SKIN NEOPLASMS