Avtor/Urednik		Scherberger, Hansjoerg; Leder, Ortwin
Naslov		Section topology and 3D-visualization of pig liver lobules
Tip		članek
Vir		Acta Stereol
Vol. in št.		Letnik 16, št. 2
Leto izdaje		1997
Obseg		str. 111-8
Jezik		eng
Abstrakt		Section topology of pig liver tissue shows that usual two-dimensional schemes do not conform to actual morphology. We demonstrate that in sections central vein lobules most frequently have pentagonal boundaries and that a strict order of periportal fields alternating in the corners of a lobule does not exist. Hence sections through lobules normally do not appear as Voronoi diagrams and, consequently, hepatocytes are not necessarily closest to the central vein of their own lobule. Computergraphic reconstruction of a liver tissue block and measurements from its digitized data showed great variability in the lobule's length, width, volume and surface. The orientation of longitudinal axis of the lobule had locally preferred directions and, as first seen in studies of section stacks, there was a general tendency of thinning towards the lobule's end. We conclude that three-dimensional structure of pig liver consists of irregular, spindle-like lobules roughly following the course of their draining vessels. This irregular three-dimensional tiling pattern can give a more realistic description of actual liver lobule composition than common regular, mainly two-dimensional models do.
Deskriptorji		LIVER BIOMETRY IMAGE INTERPRETATION, COMPUTER-ASSISTED SWINE