Avtor/Urednik     Strle, Franc; Picken, Roger N; Cheng, Yu; Cimperman, Jože; Maraspin, Vera; Lotrič-Furlan, Stanka; Ružić-Sabljić, Eva; Picken, Maria M
Naslov     Clinical findings for patients with Lyme borreliosis caused by Borrelia burgdorferi sensu lato with genotypic and phenotypic similarities to strain 25015
Tip     članek
Vir     Clin Infect Dis
Vol. in št.     Letnik 25, št. 2
Leto izdaje     1997
Obseg     str. 273-80
Jezik     eng
Abstrakt     In the course of performing culture of Borrelia burgdorferi sensu lato for the diagnosis of Lyme borreliosis in Slovenia, we encountered nine patients who infected with atypical strains. molecular analyses of these strains suggested that they were more closely related to the North American tick isolate, strain 25015 (which to the DN127 genomic group of B. burdorferi sensu lato), than they were to the three species (B. burgdorferi sensu stricto, Borrelia garinii, and Borrelia afzelii) hitherto found to be associated with European Lyme borreliosis. Review of the case histories of these patients revealed some atypical clinical features and variability in clinical presentation. In this study, we present the clinical findings for these patients and discuss their significance for the diagnosis of Lyme borreliosis. The DN127 genomic group shares with B. burgdorferi sensu stricto the distinction of being present in both the Old and New Worlds.
Deskriptorji     LYME DISEASE
BORRELIA BURGDORFERI
DNA, BACTERIAL
RNA, RIBOSOMAL, 16S
EPIDEMIOLOGY, MOLECULAR
ANTIBODIES, BACTERIAL
ELECTROPHORESIS, GEL, PULSED-FIELD
IGG
IGM
POLYMERASE CHAIN REACTION
TICKS
NORTH AMERICA
SLOVENIA