Avtor/Urednik		Šemrov, Dejan; Miklavčič, Damijan
Naslov		Izračun električnih parametrov pri elektrokemoterapiji podkožnih tumorjev miši
Prevedeni naslov		Calculation of the electrical parameters of solid tumour electrochemotherapy in mice
Tip		članek
Vir		In: Zajc B, editor. Zbornik 6. elektrotehniške in računalniške konference ERK'97. Zvezek B. Računalništvo in informatika, umetna inteligenca, robotika, razpoznavanje vzorcev - 3. letna konferenca SDRV, biomedicinska tehnika, močnostna elektrotehnika, didaktika, študentski članki; 1997 sep 25-27; Portorož. Ljubljana: Slovenska sekcija IEEE,
Leto izdaje		1997
Obseg		str. 383-6
Jezik		slo
Abstrakt		Electrochemotherapy is a novel approach in chemotherapeutic drug delivery into tumours. Short intense direct current electric pulses are applied to tumour tissue causing electropermeabilization, thus enabling entrance of chemotherapeutic drugs into cells which otherwise do not easily penetrate. A three dimensional anatomically based finite element model of the mouse with injected subcutaneous solid tumour was used to evaluate the influence of the electrode orientation on the distribution of electric field in the tumour and surrounding tissue during electrochemotherapy. Three electrode configurations, previously examined in an experimental study, were modelled. Electric field distributions were calculated for each configuration. The results of the calculation are in agreement with the results of the experimental study.
Deskriptorji		CARCINOMA, EHRLICH TUMOR ELECTRIC STIMULATION THERAPY MICE, INBRED CBA ELECTROPORATION ELECTROMAGNETIC FIELDS BLEOMYCIN