Avtor/Urednik		Sočan, Maja; Marinič-Fišer, Nataša; Kraigher, Alenka; Vidmar, Ludvik
Naslov		Etiologija pljučnice odraslih bolnikov, pridobljene v domačem okolju
Prevedeni naslov		Etiology of community-acquired pneumonia
Tip		članek
Vir		Med Razgl
Vol. in št.		Letnik 37, št. Suppl 1
Leto izdaje		1998
Obseg		str. 45-54
Jezik		slo
Abstrakt		Adult patients hospitalized with community-acquired pneumonia were prospectively studied to determine the microbial etiology of pneumonia in the period between March 1996 and April 1997. Blood and sputum samples were collected for culture. Throat swabs were taken for viral isolation and chlamydial antigen detection. Serological studies for detection of antibodies against Legionella, Mycoplasma pneumoniae, Chlamydia pneumoniae and psittaci, influenza virus types A and B, RSV, adenovirus and parainfluenza virus were performed. 211 patients were enrolled, paired sera were tested in 153 patients. In 23 (10.9%) patients blood culture was positive, S. pneumoniae was the most commonly isolated bacteria. In 44 (20.8%) patients specific antibodies comfirming acute Chlamydia pneumoniae infection were detected, in ten (4.7%) Mycoplasma pneumoniae, in six (2.8%) Legionella pneumophila, in two Chlamydia psittaci (0.9%) and Coxiella burneti in one patient. Three patients had pulmonary tuberculosis. Definitive microbial etiology was identified in 89 (49.2%) patients. Acute viral infection was comfirmed in 62 (29.4%) patients.
Izvleček		Pri odraslih bolnikih, ki so bili bolnišnično zdravljeni zaradi pljučnice, pridobljene v domačem okolju v obdobju od marca 1996 do aprila 1997, smo s prospektivno študijo poiskušali opredeliti povzročitelja pljučnice. odvzeli smo kri za hemokulturo, kulturo sputuma, bris žrela za osamitev virusa in dokaz antigena nekaterih virusov in Chlamydia pneumoniae. Naredili smo serološke preiskave za dokaz protiteles za Legionella, Mycoplasma pneumoniae, Chlamydia pneumoniae, psittaci, Coxiella burnetii, virusa influence A, B, respiratorni sincicijski virus, adenovirusa in virusa parainfluence. Vključili smo 211 bolnikov, pri 153 testirali parne serume. Pri 23 (10,9%) bolnikih smo osamili iz krvi bakterijo, največkrat S. pneumoniae. Pri 44 (20,8%) bolnikih so bila prisotna specifična protitelesa v smislu akutne okužbe s C. pneumoniae, pri desetih bolnikih (4,7%) smo dokazali mikoplazemsko pljučnico, pri šestih legionelozo (2,8%), pri dveh ornitozo (0,9%), pri enemu vročico Q. Trije bolniki so imeli tuberkulozo pljuč. Zanesljivo etiološko diagnozo pljučnice smo tako postavili pri 89 (40,7%) bolnikih. Pri 62 (29,4%) bolnikih so titri protiteles potrjevali svežo okužbo z virusi.
Deskriptorji		PNEUMONIA COMMUNITY-ACQUIRED INFECTIONS ADULT ADOLESCENCE