Avtor/Urednik		Pogačar, M; Zorko, M; Žakelj-Mavrič, M
Naslov		Substrate specificity of 17 beta-hydroxysteroid dehydrogenase from Pleurotus ostreatus
Tip		članek
Vir		Acta Chim Slov
Vol. in št.		Letnik 45, št. 1
Leto izdaje		1998
Obseg		str. 19-25
Jezik		eng
Abstrakt		We present evidence which suggests that Pleurotus ostreatus 17 beta-HSD is a pluripotent enzyme which can oxidize 17 beta-hydroxysteroids and even more so hydroquinone in the presence of NAD+. The study of the reverse reaction indicates that the carbonyl reductase activity prevailes over the hydroxysteroid dehydrogenase activity. Kinetic studies also reveal the presence of a separate acetoacetyl CoA reductase / beta-hyroxybutyryl CoA dehydrogenase activity in Pleurotus ostreatus.
Deskriptorji		17-HYDROXYSTEROID DEHYDROGENASES SUBSTRATE SPECIFICITY BASIDIOMYCETES KINETICS TESTOSTERONE TROMETHAMINE NAD GLYCERIN ANDROSTENEDIONE COENZYME A HYDROQUINONES