Avtor/Urednik		Juntes, Polona
Naslov		The number of mitoses in simple and complex type carcinomas of the mammary gland in dogs
Prevedeni naslov		Število mitoz v karcinomih mlečne žleze enostavnega in kompleksnega tipa pri psicah
Tip		članek
Vir		Radiol Oncol
Vol. in št.		Letnik 32, št. 1
Leto izdaje		1998
Obseg		str. 77-82
Jezik		eng
Abstrakt		According to the WHO classification mammary gland tumours in dogs are classified into simple and complex type. General opinion is that the complex type carcionomas have better prognosis than the simple type carcinomas. The aim of this research was to quantify and compare the mitotic activity in both types of carcinomas. Sixty-five simple type and 99 complex type carcinomas were included in the study and two methods for counting of mitoses were compared: mitotic activity index (MAI) and number of mitoses ner square millimetre (M/mm2). Both methods showed significant (P=0.0001 for MAI; and P=0.0089 for M/mm2) differences between simple and complex type carcinomas with respect to the number of mitoses. The number of mitoses in individual tumours varied from 0 to 95 per ten high power fields in simple type carcinomas and from 0 to 57 in complex type carcinomas. The average number of mitoses was higher when only one tumours was present and lower when there multiple tumours. Our results confirm the lower mitotic potential of the epithelial parts of complex type mammary gland carcinomas in comparison with simple type carcinomas. This fact certainly contributes to better prognosis of the disease, especially if myoeptihelial cells are a predominant component of the tumour.
Deskriptorji		MAMMARY NEOPLASMS MITOTIC INDEX DOGS