Avtor/Urednik		Kompan, Lidija
Naslov		Vpliv zgodnje enteralne prehrane na proces translokacije bakterij in odpovedovanje organskih sistemov pri politravmatiziranih poškodovancih
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Medicinska fakulteta
Leto izdaje		1998
Obseg		str. 68
Jezik		slo
Abstrakt		Objective. Multiple organ failure (MOF) remains an important cause of latc morality in intensive care patients. It is due to excessive release of inflammatory substances, bacteria and endotoxins can help it when they translocate the gut. Therefore it is important to maintain gut mucosal integrity by enteral feeding. Methods. We studied prospectively 28 adult patients with polytrauma who were admitted in shock. Group A comprised 14 polytrauma patients who were started on enteral tube feeding immediately after recovery from shock or no later than 6 hours after admission to Central IClJ. Group B consisted of 14 polytraumatised patients in whom enteral feeding was instituted later than 24 hours after admission. Lactulose-mannitol (L/M) test was done on the dav 2 and 4 after trauma, while MOF score was determined daily. Results. The groups were matched for age, injury severity score and duration and severitv of shock. Group A patients were started on enteral feeding in average 9,35 hours. and group B patients 45, 13 hours after trauma respectively. Group A received more food even on the seventh day after trauma. Average late MOF score in group A was 1,84 versus 2,8I in group B (p<0,002) and for the entire series of 28 polytrauma patients positive correlation was found between the late MOF and the time the enteral nutrition started but not the volume of the food received. The average liver failure seore in group A was 1,0 in group B 1,59 (p< 0,003) The average L/M index in healthy volunteers was 0,0164. On the second day after trauma L/M index in polytraumatised patients group A was in average 0,0358 and on the fourth day 0,0317. in group B on the second day 0,0887 and on the fourth 0,1650. (Abstract truncated at 2000 characters)
Deskriptorji		MULTIPLE TRAUMA MULTIPLE ORGAN FAILURE ENTERAL NUTRITION BACTERIAL TRANSLOCATION INTENSIVE CARE UNITS ENDOTOXINS PROSPECTIVE STUDIES SHOCK LACTULOSE MANNITOL LIVER FAILURE