Avtor/Urednik		Noth, J; Brook, GA; Nacimiento, W
Naslov		Reorganization and repair after injury to the spinal cord
Tip		članek
Vir		In: Stalberg EV, de Weerd AW, Zidar J, editors. ECCN 98. 9th European congress of clinical neurophysiology; 1998 Jun 4-7; Ljubljana. Bologna: Monduzzi Editore,
Leto izdaje		1998
Obseg		str. 473-8
Jezik		eng
Abstrakt		The spontaneous reorganisational events which take place at the lesion site following experimental spinal cord injury have been investigated. Spinal cor compression caused massive destruction of neuronal and glial elements at the site of injury. The lesion site became heavily infiltrated by neutrophils, macrophages and also Schwann cells. From 7-14 days after injury, there was a period of substantial axonal ingrowth into the lesion. This axonal regeneration displayed an overall longitudinal orientation and was spatially correlated with overlapping and longitudinally orientated Schwann cells and processes. Many regenerating axons were GABA- and glycine-immunoreactive, but surprisingly few were found to be CGRP- or substance P-positive. These data suggest that, under some conditions, the spontaneous tissue repair processes of the injured spinal cord are capable of providing a suitable framework for orientated nerve fibre regeneration.
Deskriptorji		SPINAL CORD INJURIES NERVE REGENERATION RATS, WISTAR