Avtor/Urednik		Lefaucheur, JP; Bachoud-Levi, AC; Cesaro, P; Degos, JD; Peschanski, M; Lisovoski, F
Naslov		Correlations between electrophysiological data and clinical scores in Huntington's disease
Tip		članek
Vir		In: Stalberg EV, de Weerd AW, Zidar J, editors. ECCN 98. 9th European congress of clinical neurophysiology; 1998 Jun 4-7; Ljubljana. Bologna: Monduzzi editore,
Leto izdaje		1998
Obseg		str. 695-9
Jezik		eng
Abstrakt		We studied 31 patients with Huntington's disease (HD) of grade 1 or 2 (appreciated by Dhoulson's Score), by recording palmar sympathetic skin responses (SSR), blink reflexes (BR), thenar long latency reflexes (LLR), cortical somatosensory evoked potentials (SEP), and electromyographic silent period (SP) evoked by transcranial magnetic stimulation. All but one patients exhibited at least one abnormal test (97%). SEP were abnormal in 87% of patients, BR in 48%, SSR in 52%, LLR in 39%, and SP in 58%. Electrophysiological results correlated with the motor score of the Unified Huntington's Disease Rating Scale (UHDRS), but not with the Mattis Dementia Rating Scale (MDRS). The electrophysiological tests, particularly SEP, can reveal early deterioration in multiple neural systems in the course of HD.
Deskriptorji		HUNTINGTON'S DISEASE SKIN SYMPATHETIC NERVOUS SYSTEM BLINKING EVOKED POTENTIALS, SOMATOSENSORY ELECTROMYOGRAPHY MAGNETICS