Avtor/Urednik		Švigelj, Viktor; Meglič, Bernard; Grad, Anton
Naslov		Možganska kap in tromboliza - vloga urgentne službe
Prevedeni naslov		Acute stroke and thrombolysis - the importance of the emergency services
Tip		članek
Vir		In: Bručan A, Gričar M, editors. Urgentna medicina: izbrana poglavja 4. Zbornik 5. mednarodni simpozij o urgentni medicini; 1998 jun 17-20; Portorož. Ljubljana: Slovensko združenje za urgentno medicino,
Leto izdaje		1998
Obseg		str. 253-63
Jezik		slo
Abstrakt		Thrombolytic therapy has been used in patients with acute ischemic stroke to restore cerebral blood flow, reduce ischemia, and reduce neurologic disability. The hypothesis is that recanalisation of an occluded cerebral artery may assist the recovery of reversible ischemic tissue. During the past decade several thrombolytic substances have been tested in uncontrolled trials, with either intraarterial or intravenous administration. Early studies using thrombolysis for acute stroke proved disappointing (therapy first attempted in 1950's and 1960's), because they were poorly controlle dand often included the wrong type of stroke patients, and mainly because it was not stipulated that patients should be treated within six hours of the stroke. The reason was also the absence of good imaging techniques, which meant that patients with hemorrhagic strokes are likely to have been included. The European Cooperative Acute Stroke Study was the first large-scale, couble-blind, placebo controlled study designed to asses the efficacy and safety of the thrombolytic therapy in acute ischemic stroke patients. Second important study is conducted by the National Institute of Neurological Disorders and Stroke - NINDS. Firstly, the purpose of our presentation is to present shortly those studies concerning thrombolysis in an acute ischemic stroke, the Helsingborg Declaration and the NINDS's Consensus on Rapid Identification and Treatment of Acute Stroke. Secondly, we prsent our experiences with thrombolytic treatment in acute stroke patients, and the least but not the last and most important, the role of the Emergency Services in management of the acute stroke patients, specially those in whom thrombolytic therapy could be administered. The importance of these facts is hown also by the results of our one-month trial. We assesed the features of arrival of patients with acute stroke to our Department in June 1997.(Abstract truncated at 2000 characters.)
Deskriptorji		CEREBROVASCULAR DISORDERS EMERGENCIES EMERGENCY MEDICAL SERVICES THROMBOLYTIC THERAPY TREATMENT OUTCOME