Avtor/Urednik		Mueller-Premru, Manica
Naslov		Preučevanje načinov bakterijske okužbe žilnih katetrov pri novorojenčkih v enoti za intenzivno terapijo
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Medicinska fakulteta
Leto izdaje		1998
Obseg		str. 96
Jezik		slo
Abstrakt		Microorganisms present on the outer surface of peripheral and central venous catheters (CVC) are thought to originate from patient's skin and presumably play an important part in catheter infections. Bacteria occuring on the inner catheter surface probably originate from the catheter stopcock or from fluid mixture used for parenteral nutrition; their role in catheter infections is less clear. The most frequent aetiologic agents of catheter infections are coagulase-negative staphylococci (CNS). These bacteria can also be found on patient's skin as a part of normal microbial flora. We studied the pathogenesis of CVC infections in newborns treated in pediatric intensive care unit. The aim of our study was to determine whether stopcocks may become infected, and whether bacteria from stopcocks can infect catheter tips and cause catheter-related sepsis (CRS). In the first part of the study, we observed infections during routine procedure of catheter care. In the second part, we introduced measures to prevent stopcock and catheter infections (aseptic assembly and protection of stopcocks, change of stopcock every three days, use of irreversible valves) and evaluated their efficacy. Forty-nine mature newborns and prematures (gestational age grom 26. to 37. weeks) were included in the study. All showed clinical deterioration and some had positive blood culture or laboratory parameters of sepsis (increased CRP, leucocytosis or leucopenia, increased premature/total neutrophil ratio, thrombocytopenia). All patients had multi-purpose multi-lumen CVC, which were removed. Six specimens were taken for culture in each patient: the stopcock, the catheter tip, the intradermal segment (IDC), a swab taken from the tkin surrounding the puncture site, sample of fluid mixture and blood.(Abstract truncated at 2000 characters.)
Deskriptorji		INTENSIVE CARE UNITS, NEONATAL CATHETERIZATION, CENTRAL VENOUS CATHETERIZATION, PERIPHERAL EQUIPMENT CONTAMINATION INFANT, NEWBORN VEINS BACTERIA STAPHYLOCOCCUS SEPSIS PARENTERAL NUTRITION CROSS INFECTION