Avtor/Urednik		Križman, Igor; Kozjek, Franc; Primožič, Stanislav
Naslov		Randomized double-blind study of lansoprazole and ranitidine in the treatment of the patients with duodenal ulcer
Prevedeni naslov		Randomizirana, dvojno slepa študija učinkovitosti lanzoprazola in ranitidina pri zdravljenju bolnikov z duodenalnim ulkusom
Tip		članek
Vir		Acta Pharm Zagreb
Vol. in št.		Letnik 48, št. 3
Leto izdaje		1998
Obseg		str. 193-99
Jezik		eng
Abstrakt		To study lansoprazole (30 mg, daily once) by comparison with ranitidine (300 mg, daily once) in patients with duodenal ulcer, a randomized, double-blind trial was set up in seven hospitals in Slovenia and Croatia. Evaluation was based on clinical outcome in 92 patients. There was a statistically significant difference between the time interval of disappearance of duodenal ulcer achieved by treatment with lansoprazole and ranitidine although the disappearance of troubles seems the same for both drugs.
Izvleček		V multicentrični, randomizirani in dvojno slepi klinični študiji je bila proučevana učinkovitost lanzoprazola (30 mg dnevno) v primerjavi z ranitidinom (300 mg dnevno) pri 92 bolnikovih z duodenalnim ulkusom. Rezultati kažejo statistično značilne razlike v hitrosti celjenja ulkusa, ki ju povročita zdravili. V subjektivni oceni izgubljanja težav pa je skupina bolnikov zdravljenih z lanzoprazolom ni razlikovala od skupine bolnikov, ki so bili zdravljeni z ranitidinom.
Deskriptorji		DUODENAL ULCER RANITIDINE BENZIMIDAZOLES DOUBLE-BLIND METHOD TREATMENT OUTCOME