Avtor/Urednik		Vesnaver, Aleš
Naslov		Zdravljenje poobsevalnih okvar s hiperbarično oksigenacijo
Tip		monografija
Kraj izdaje		Ljubljana
Založnik		Medicinska fakulteta
Leto izdaje		1998
Obseg		str. 44
Jezik		slo
Abstrakt		Therapy of post-irradiation injuries is a field where hyperbaric oxygenation (HBO) has proved to be very effective. As HBO therapy in Slovenia is a new field, the goal of this study was to evaluate its usefulness and effectiveness in patients who had been previously irradiated for carcinomas of the oral cavity and pharynx. Patients with post-irradiation injuries treated with HBO were compared with those treated without HBO. In this way, two groups of patients with post-irradiation caries (PIC) who needed dental extractions were compared, the test group (n=5) being treated with the aid of HBO, and the control group (n=5) without HBO. Similarly, two groups of patients with osteoradionecrosis (ORN) of the mandible were compared, again the test group (n=5) treated with HBO, and the control group (n=7) without HBO. A comparison was conducted between matching groups regarding the fnal result and time of treatment, the number of hospitalisations, the total number of hospital days, and the total price of treatment. The final result and time of treatment were statistically significantly (p < 0,01 ) better in the HBO group, both in PIC and ORN patients, as compared to controls. The number of hospitalisations did not differ significantly between both groups of patients with PIC, whereas it was signifcantly (p < 0,05) smaller in the HBO group of patients with ORN. The total number of hospital days was insignificantly greater in the HBO group of patients with PIC, and insignificantly smaller in the HBO group of patients with ORN. The total price of treatment was significantly (p < 0,05) greater in the HBO group of patients with PIC, and insignificantly smaller in the HBO group of patients with ORN. Based on the results, it is concluded that HBO therapy improves therapy of post-irradiation injuries. The quality and rate of wound healing improve, which makes therapy of these injuries faster and, at least in ORN patients, cheaper.
Deskriptorji		MOUTH NEOPLASMS PHARYNGEAL NEOPLASMS DENTAL CARIES OSTEORADIONECROSIS HYPERBARIC OXYGENATION RADIOTHERAPY MANDIBULAR DISEASES HOSPITALIZATION RADIATION INJURIES HEALTH CARE COSTS WOUND HEALING