Avtor/Urednik		Orožim, E
Naslov		Treatment of Microsporum canis infected cats with terbinafine
Tip		članek
Vir		Acta Dermatovenerol Alp Pannon Adriat
Vol. in št.		Letnik 7, št. 3-4
Leto izdaje		1998
Obseg		str. 157-63
Jezik		eng
Abstrakt		Terbinafine is a new allylamine antifungal agent with its primary characteristic of fungicidal action. Because of its excellent wualities this drug is interesting for use in veterinary medicine too. Among the diseases, which are common in humans and animals, we are dealing with the effective control of Microsporum canis infection. Humans are often infected by contact with cats. The most dangerous cources of infection are stray cats and asymptomatic carriers. Because an effective vaccine against the disease is still not available, it is important to detect infected cats and treat them. Due to excellent results in humans it is reasonable to use the terminafine. Our preliminary results using terbinafine in cats showed that cats tolerated terbinafine well in a dosage of 10-20 mg/kg daily for 5 months. Half of the cats got cured in 145 days, an all were cured in 159 days. It is too early to estimate the result of such treatment, but according to our clinical experience with the combination of drugs, we would expect shortet treatment periods from a fungicidal agent. It is highly probable that the dose 10-20 mg/kg in cats acts fungistatically and that higher doses should also be tried.
Deskriptorji		DERMATOMYCOSES MICROSPORUM CATS TREATMENT OUTCOME