| Avtor/Urednik | Markež, Jernej; Mulej, Marija; Zaletel, Janez; Rus, Igor; Arnež, Teja; Resman, Janez | |
| Naslov | Opredelitve učinka hemodialize z doplersko ehokardiografsko analizo hitrosti mitralnega in pulmonalnega venskega pretoka | |
| Prevedeni naslov | Effects of hemodialysis on left ventricular diastolic filling: transthoracic Doppler echocardiographic analysis of mitral and pulmonary venous flow velociity patterns | |
| Tip | članek | |
| Vir | Zdrav Vestn | |
| Vol. in št. | Letnik 68, št. 2 | |
| Leto izdaje | 1999 | |
| Obseg | str. 85-92 | |
| Jezik | slo | |
| Abstrakt | Background. Pulsed Doppler echocardiography (PDE) was used to evaluate the velocity and other filling parameters of left atrium (LA) and left ventricle (LV), enabling us to estimate the diastolic function of LV. The velocity curves are influenced not only by the diastolic properties of LV (relaxation, compliance) but also by the preload. Hemodialysis (HD) causes acute decrease of intravascular volume and the preload. The aim of this study was to determine the effect of HD on PDE variables of the transmitral and pulmonary vein flow. Methods. The study group consisted of 27 patients on maintenance HD (17 women and 10 men; aged 22 to 73 years, mean 54+-14 years). The inclusion criteria were: sinus rhythm, heart rate 50 do 90 beats/min., normal LV systolic function (shortening fraction - 5 FS above 30%), absence of history of myocardial infarction, no significant valvular disease, adequate transthoracic recordings of pulmonary venous flow velocity. The duration of HD treatment was 1 to 13 years, on average 5.7 years. Patients were examined immediately before and after the same standrd bicorbonate HD. Patients underwent clinical examination, M-mode, two-dimensional and Doppler echocardiography. Results. 18 pats (67%) had LV hypertrophy (LV mass index after HD: 141.3+-54.0 g/m2). After HD the body weight was decreased from 61.2+-9,1 kg to 59.3+-9 kg (p < 0.05). Heart rate and blood pressure did not changes significantly during HD. Diastolic diameter of LV was decreased from 53.7+-to 50.4+-6.6 mm (p < 0.001),% FS was not changes. (Abstract truncated at 2000 characters) | |
| Izvleček | Izhodišča. Neinvazivni prikaz hitrosti in razporeditve polnitve levega preddvora (LA) in prekata (LV) s pulzno doplersko ehokardiografijo (PDE) omogoča oceno diastolične funkcije. Na krivulje hitrosi ne vplivajo samo diastolične lastnosti LV (relaksacija, podajnost (kompliancal)), ampak tudi preload. Hemodializa (HD) povzroči akutno zmanjšanje znotrajžilnega volumna in preloada. Namen raziskave je opredelitev učinka HD na PDE spremeljivke hitrosti transmitralnega in pulmonalnega venskega pretoka. Metode. V študijo smo vključili 27 bolnikov s končno odpovedjo ledvic (KLO) v programu kronične HD (17 žensk in 10 moških v starosti od 22 do 73 let; povprečje 54+-14 let). Vključitveni kriteriji so bili: sinusni ritem, srčma frekvenca med 50 in 90/min, normalna sistolična funkcija LV (delež sistolične skrajšave - % FS nad 30%), bolniki brez prebolelega miokardnega infarkta, stenoze aortne zaklopke, pomembne mitralne insuficience ter ustrezen transtorakalni PDE prikaz hitrosti pretoka v pljučni veni. Trajanje HD je od enega do 13 let, povprečno 5,7 leta. Bolnikom smo tik pred standardno bikarbonatno HD in takoj po njej naredili klinični pregled, enodimenzionalno (1D), dvodimenzionalno (2D) in doplersko ehokardiografijo. Rezultati. Hipertrofijo LV, opredeljeno kot zvišan indeks mase LV po HD, ima 18 bolnikov (67%). Telesna teža po HD se je zmanjšala od 62,2+-9,1 kg do 59,3+-9 kg (p < 0,05). Med srčno frekvenco, krvnim tlakom pred in po HD ni bilo pomembne razlike. Diastolični premer LV se je zmanjšal od 53,7+-5,0 mm do 50,4+-6,6 mm (p < 0,001),% FS se ni spremenila.(Izvleček prekinjen pri 2000 znakih) | |
| Deskriptorji | HEMODIALYSIS VENTRICULAR FUNCTION, LEFT ECHOCARDIOGRAPHY, DOPPLER STROKE VOLUME BLOOD FLOW VELOCITY |