Avtor/Urednik		Skok, Pavel
Naslov		Načela zdravljenja gastroezofagealne refluksne bolezni
Prevedeni naslov		Principles of treatment in gastroesophageal reflux disease
Tip		članek
Vir		In: Hojs R, Krajnc I, editors. Zbornik predavanj in praktikum 10. srečanje internistov in zdravnikov splošne medicine Iz prakse za prakso z mednarodno udeležbo; 1999 maj 21-22; Maribor. Maribor: Spošna bolnišnica Maribor,
Leto izdaje		1999
Obseg		str. 237-51
Jezik		slo
Abstrakt		Gastroesophageal reflux disease is a chronic disease associated with frequent relapses. The majority of patients experience symptoms occasionally, but there is also a group of patients in whom the complaints are of permanent nature. Symptom evaluation is of key importance, as it is the most cost-effective and sensitive method for diagnosis of the disease and for adjustement of initial and long-term therapy for individual patient. Endoscopy is an important adjunct to symptom assesment. Different drugs, having miscellaneous modes of action, are used in the therapy of reflux disease: antacids, anti-secretory drugs and prokinetics. Only the proton pump inhibitors omeprazol, lansoprazol in pantoprazol are highly effective with all grades of gastroesophageal reflux disease. Additional factors having an important role in the treatment of this disease are dietary measures and change of lifestyle. Frequent relapses of the disease necessitate long-term maintenance treatment. If medical therapy fails, laparoscopic antireflux surgery must be considered. All current therapies have shortcomings. Management strategies should identify the most effective treatment that gives adequate relief of symptoms and so corrects any symptom-related impairment of quality of life.
Deskriptorji		GASTROESOPHAGEAL REFLUX ANTACIDS HISTAMINE H2 ANTAGONISTS OMEPRAZOLE METOCLOPRAMIDE