Avtor/Urednik     Čemažar, Maja
Naslov     Predictive assays of tumor response to chemo and radiotherapy
Prevedeni naslov     Napovedni testi za izid zdravljenja tumorjev po kemo in radioterapiji
Tip     članek
Vir     Radiol Oncol
Vol. in št.     Letnik 33, št. 2
Leto izdaje     1999
Obseg     str. 127-36
Jezik     slo
Abstrakt     Currently used predictive assays of treatment outcome of tumors treated by chemo- or radiotherapy and radiation damage of normal tissues are presented. This review is focused on the assays where tumor cells derived from the human tumors need to be cultured in in vitro conditions to perform the test. In addition, an overview of the clinical studies dealing with the correlation between predictive assays and treatment out-come or radiation damage to the normal tissues is given.
Izvleček     Predstavljeni so testi za napovedovanje izida zdravljenja tumorjev po kemo- in radioterapiji in poškodb normalnih tkiv po radioterapiji. Pregled je osredotočen na tiste teste, pri katerih je treba celice gojiti v pogojih in vitro. Poleg tega članek obravnava tudi korelacijo med napovednimi testi in izidom zdravljenja različnih vrst raka ter poškodbami normalnih tkiv.
Deskriptorji     SARCOMA, EXPERIMENTAL
NEOPLASMS
RADIATION INJURIES
CELL SURVIVAL
DNA DAMAGE
MICE
MICRONUCLEUS TESTS
CHROMOSOMES
CELL DEATH
GENE EXPRESSION
ANOXIA
TREATMENT OUTCOME