Avtor/Urednik		Stabej, P; Domanjko-Petrič, A
Naslov		Dilatativna kardiomiopatija pri psih
Prevedeni naslov		Dilated cardiomyopathy in dogs
Tip		članek
Vir		Zb Vet Fak Univ Ljublj
Vol. in št.		Letnik 36, št. 1
Leto izdaje		1999
Obseg		str. 101-10
Jezik		slo
Abstrakt		The aim of this research was the analysis of dilated cardiomyopathy in dogs at the Clinic for Surgery and Small animals of the Veterinary Faculty in Ljubljana in the time between October 1992 and September 1997. In a period of five years 52 cases of dilated cardiomyopathy in dogs were diagnosed. The majority of dogs were Doberman pinschers (40.4 % ) and German shepherds (13.5 % ). Amongst Doberman pinschers males predominated (76.2 % males, 23.8 % females), as well as amongst other breeds (84 % males,16 % females). The average survival time in Doberman pinschers was in comparison to other breeds significantly shorter (50 days and 147 days). Thirteen (62 %) Doberman pinschers died or were euthanised in congestive heart failure, seven (33 % ) died suddenly and one died because of gastric dilatation with mesenteric torsion. All Doberman pinschers in congestive heart failure had decreased shortening fraction (from 1.4 % to 18 % ), which was lower than shortening fraction of dogs that died suddenly (from 8 % to 27 % ). Ventricular premature complexes were found in two Doberman pinschers that died suddenly and in four Doberman pinschers that were in congestive heart failure. On the basis of pedigree analysis three modes of inheritance are possible: autosomal dominant, mitochondrial or linked to X-chromosome.
Izvleček		Predmet raziskave je bila analiza primerov dilatativne kardiomiopatije, ki so bili ugotovljeni pri psih na Kliniki za kirurgijo in male živali Veterinarske fakultete v obdobju od oktobra 1992 do septembra 1997. Dokazanih primerov dilatativne kardiomiopatije pri psih je bilo v obdobju petih let na omenjeni kliniki 52. Med psi je bilo največ dobermanov (40,4 %) in nemških ovčarjev (13,5 %). Od obolelih dobermanov je bilo 76,2 % samcev in 23,8 % samic, pri psih ostalih pasem je bilo samcev 84 % in samic 16 % . Povprečna doba preživetja dobermanov je bila znatno krajša kot povprečna doba psov drugih pasem (50 oz.147 dni). Dobermanov, ki so poginili ali bili usmrčeni zaradi kongestivnega srčnega popuščanja, je bilo trinajst (62 %), nenadno jih je poginilo sedem (33 %), eden pa je poginil zaradi razširitve in zasuka želodca. Vsi dobermani s kongestivnim popuščanjem srca so imeli znižano sistolično skrajšanje (1,4-18 %), ki je bilo nižje od sistoličnega skrajšanja nenadno poginulih dobermanov (8-27 %). Prekatne prezgodnje utripe smo ugotovili pri dveh nenadno poginulih dobermanih in pri štirih dobermanih s kongestivnim popuščanjem srca. Na podlagi analize rodovnikov sklepamo, da gre za tri možne načine dedovanja: avtosomalno dominantno, vezano na X-kromosom in mitohondrijsko.
Deskriptorji		CARDIOMYOPATHY, CONGESTIVE DOGS ELECTROCARDIOGRAPHY ECHOCARDIOGRAPHY PEDIGREE HEART FAILURE, CONGESTIVE