Avtor/Urednik     Košak, Robert; Antolič, Vane
Naslov     Eritromelalgija
Prevedeni naslov     Erythromelalgia
Tip     članek
Vir     Med Razgl
Vol. in št.     Letnik 38, št. 2
Leto izdaje     1999
Obseg     str. 233-7
ISSN     0025-8121
Jezik     slo
Abstrakt     Erythromelalgia is a rare syndrome characterised by attacks of severe burning pain, erythema, and warmth of the extremities-primarily the feet and, to a lesser extend, the hands. The distress is induced by environmental heat, exercise, and dependency; it is relieved by exposure to cold and elevation of the extremity idiopathic and secondary forms of erythromelalgia exist. Secondary erythromelalgia has been linked to a wide variety of diseases, the most common of which are certain myeloproliferative disorders. This type affect aduns only, and is dramaticcally ameliorated by small doses of aspirin. Intravascular pratelet, with plugging of arterioles have been suggested as the cause of erythromelalagia in nyeloproliferative disorders. The pathogenesis of idiopathic forms has not yet been delineated.
Izvleček     Eritromelalgija je redka bolezen z značilnimi ponavljajočimi se napadi žgočih bolečin, eritema in povišane temperature okončin, predvsem nog, redkeje rok. Napad navadno izzove segrevanje, fizična aktivnost ali določen položaj okončine. Značilno je olajšanje klinične slike po hlajenju in dvigu uda. Ločimo primarno in sekundarno obliko eritromelalgije. Sekundarna oblika se pojavlja kot posledica drugih obolenj, predvsem mieloproliferativnih bolezni. Ta tip prizadene le odraslo populacijo in se učinkovito zdravi z majhnimi odmerki aspirina. Vzrok obolenja pri tej obliki je najverjetneje intravaskularna aktivacija in agregacija trombocitov in posledično delna ali popolna zapora arteriol. Patogeneza pri primarni obliki ni poznana.
Deskriptorji     ERYTHROMELALGIA