Avtor/Urednik		Vrtačnik-Bokal, E; Meden-Vrtovec, H
Naslov		Utero-ovarian arterial blood flow and hormonal profile in patients with polycystic ovary syndrome
Tip		članek
Vir		Hum Reprod
Vol. in št.		Letnik 13, št. 4
Leto izdaje		1998
Obseg		str. 815-21
Jezik		eng
Abstrakt		Utero-ovarian arterial blood flow and hormonal profile were evaluated in 20 patients with polycystic ovary syndrome (PCOS) and in 22 patients with normal menstrual cycle (NMC) undergoing in-vitro fertilization )IVF) treatment. In this controlled prospective clinical study the vascular impedance in the utero-ovarian arteries was measured in both groups on days 4,13,22(introduction of gonadotrophin releasing hormone agonist (GnRHa) administration), 36 (after the 14 day GnRHa administration) and on the day of human chorionic gonadotrophin (HCG) administration. Simultaneously, serum concentrations of luteinizing hormone (LH), follicle stimulating hormone (FSH), oestradiol, androstendione and sex hormone-binding globulin (SHBG) were determined. In the PCOS group significantly (P<0.05) higher concentrations of FSH and LH were found on day 22, whereas the excess of androstendione production and lower SHBG values were registered throughout the stuudied cycles. Also, no effect of the 14 day GnRHa administration on the androstendione discharge was regostried. In both groups the serum LH concentration decreased significantly (P<0.05); however, the value remained significantly (P<0.05) higher in the PCOS group. In the PCOS group no changes regarding the vascular impedance in the uterine artery were registered in the phase of the cycle procesing the GnRHa administration. The resistance index (RI) on day 22 of the cycle was 0.86 in the PCOS and 0.82 in the NMC group. In the NMC group the active ovary showed dramatic changes during the cycle, with vaascular impedance almost constant throughout the cycle in the inactive ovary. In the PCOS group the vascular impedance to ovarian arterial blood flow in both ovaries was similar to that in inactive ovaries in the NMC group. (Abstract truncated at 2000 characters).
Deskriptorji		POLYCYSTIC OVARY SYNDROME OVARY UTERUS FERTILIZATION IN VITRO BLOOD FLOW VELOCITY GONADORELIN GONADOTROPINS, CHORIONIC HEMODYNAMICS PROSPECTIVE STUDIES REGIONAL BLOOD FLOW ULTRASONOGRAPHY, DOPPLER, COLOR