Avtor/Urednik		Zidar, Nina; Volavšek, Metka; Trček, Ciril; Kern, Izidor; Gale, Nina
Naslov		Wegener's granulomatosis in upper respiratory tract
Tip		članek
Vir		In: Vizjak A, Rozman B, Ferluga D, editors. Autoimmune systemic diseases. Proceedings of the 30th memorial meeting for professor Janez Plečnik; 1999 Dec 2-3; Ljubljana. Ljubljana: Faculty of medicine, Institute of pathology,
Leto izdaje		1999
Obseg		str. 21-4
Jezik		slo
Abstrakt		Wegener's granulomatosis is a distinct clinico-pathologic entity characterised by granuloma formation in the upper and lower respiratory tracts, necrotizing vasculitis of small arteries and veins, and necrotizing glomerulonephritis. The vast majority of patients have antineutrophil cytoplasmic antibodies in the serum with the characteristic cytoplasmic pattern (C-ANCA). However, in early phases of the disease only the upper respiratory tract can be affected, clinical and histological features can be nonspecific, and ANCA test negative. In this paper, we present the involvement of the upper respiratory tract in patients with early of limited WG. We emphasise the significance of clinical, histological, and serological parameters in early detection of WG.
Deskriptorji		WEGENER'S GRANULOMATOSIS RESPIRATORY TRACT DISEASES ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC BIOPSY SLOVENIA VASCULITIS