Avtor/Urednik		Jensterle, Jože; Mlakar, Janez; Vodušek, David B; Frith, Chris D
Naslov		Disorganisation in schizophrenia need not result from a failure to inhibit dominant response tendencies
Tip		članek
Vir		Cogn Neuropsychiatry
Vol. in št.		Letnik 5, št. 2
Leto izdaje		2000
Obseg		str. 105-21
Jezik		slo
Abstrakt		Schizophrenic disorganisation syndrome is ussually considered to be associated with poor perfomance on frontal lobe tasks, specifically those that require suppression of dominant responses. Two cases are presented who do not fulfil this expectation Despite severe disorganisation of speech and behaviour these patients performedwell on several executive tasks in which dominant responses had to besupressed. One of the patients showed significantly less interference on the Stroop task than normal controls. In contrast, both patients performed badly on a sentence completion task in which production of the dominant response was appropriate. These observations imply that these patients were able to exert "top-down" supervisory control in situations where it was necessary to inhibit dominant response tendencies. We propose that, although many patients with schizophrenia and intellectual deficits do show disorganised behaviour is a consequence of the failure of "bottom-up" control by context. Our cases indicate that disorganisation in schizophrenia may be associated with different underlyng cognitive deficits.
Deskriptorji		SCHIZOPHRENIA, DISORGANIZED SCHIZOPHRENIC PSYCHOLOGY ADULT INTELLIGENCE TESTS NEUROPSYCHOLOGICAL TESTS INTERVIEW, PSYCHOLOGICAL