Avtor/Urednik     Meissner, Markus; Stark, Klaus; Črešnar, Bronja; Kirk, David L.; Schmitt, Ruediger
Naslov     Volvox germline-specific genes that are putative targets of RegA repression encode chloroplast proteins
Tip     članek
Vir     Curr Genet
Vol. in št.     Letnik 36, št. 6
Leto izdaje     1999
Obseg     str. 363-70
Jezik     eng
Abstrakt     In Volvox carteri, regA acts as a master gene to suppress all germ cell functions in somatic cells. Its product, RegA, has features of a transcriptional repressor. Here we report cDNA sequences representing I S nuclear genes with properties expected of RegA targets: they are expressed strongly in germ cells and in regA-, but not regA+, somatic cells. Two of them encode polypeptides with no recognizable features, but ten (like three previously sequenced ones) encode chloroplast proteins of known function, and the remaining three encode putative chloroplast proteins of unknown function. This suggests that RegA blocks reproductive development in somatic cells by preventing chloroplast biogenesis, thereby making it impossible for the cells to grow enough to reproduce.
Deskriptorji     ALGAE, GREEN
CHLOROPLASTS
GENE EXPRESSION REGULATION, PLANT
AMINO ACID SEQUENCE
DNA, COMPLEMENTARY
CLONING, MOLECULAR
GERM CELLS
PHOTOSYNTHETIC REACTION CENTER, PLANT
REGULATORY SEQUENCES, NUCLEIC ACID
TRANSLATION, GENETIC
IRON-SULFUR PROTEINS
MOLECULAR SEQUENCE DATA
OPEN READING FRAMES
PHOSPHOGLYCERATE KINASE