Avtor/Urednik		Boršoš, Imre; Podboj, Jernej
Naslov		Naše izkušnje pri zdravljenju bolnikov z aspirinsko intoleranco
Prevedeni naslov		Our experiences with the treatment of patients with aspirin intolerance
Tip		članek
Vir		Med Razgl
Vol. in št.		Letnik 39, št. Suppl 3
Leto izdaje		2000
Obseg		str. 261-4
Jezik		slo
Abstrakt		Introduction: Aspirin intolerance is a clearly-defined clinical syndrome with distinct clinical features. Clinically, the aspirin intolerance syndrome presents with rhinitis, nasal polyposis and asthma. Diagnosis is based on the history and clinical picture. Treatment is medical and surgical. Patients: The study was based on the follow-up of patients treated from 1987 to 1999. There were 727 patients, 132 of whom had aspirin intolerance. All patients were treated using both drugs and surgery. Results: Of 595 patients with nasal polyps and without aspirin intolerance, 79% were male and 21% female; of 132 with nasal polyps and aspirin intolerance, 21% were male and 79% female. In patients with AI, more recurrences (60%) were observed than in those without aspirin intolerance (32%). There were 1 major and 5 minor complications. Discussion: The importance of correct diagnosis, correct medical and surgical treatment and continuous co-operation between the doctors and the patient are emphasised. Every patient must be treated individually with drugs and, if necessary, with surgery. Asthma must be treated as well.
Izvleček		Uvod. Aspirinska intoleranca je poseben klinični sindrom z jasno klinično sliko. V klinični sliki je izrazito vnetje nosu z izcedkom iz nosu, kongestijo in nosno polipozo ter bronhialno astmo. Diagnoza temelji predvsem na anamnezi in klinični sliki, zdravljenje pa poteka z zdravili in operacijsko. Bolniki. Prikazujemo bolnike z nosno polipozo, zdravljenje na kliniki za otorinolaringologijo in cervikofacialno kirurgijo v Ljubljani od leta 1987 do leta 1999. Od 727 bolnikov jih je bilo 132 z aspirinsko intoleranco. Vsi so bili zdravljeni z zdravili in operacijsko. Rezultati. Pri 595 bolnikih z nosno polipozo brez aspirinske intolerance je bilo 79 % moških in 21% žensk, medtem ko je bilo med 132 bolniki z aspirinsko intoleranco razmerje med spoloma ravno obratno - 21 % je bilo moških in 79 % žensk. Izmed 595 bolnikov z nosno polipozo brez aspirinske intolerance je bilo ponovno operiranih 194 (32 %), pri bolnikih z aspirinsko intoleranco pa 80 (60%). Pri bolnikih z aspirinsko intoleranco smo imeli 1 hudo in 5 lahkih pooperacijskih zapletov. Zaključki. Poudarjena je pomembnost pravilne diagnostike, pravilnega kirurškega zdravljenja in zdravljenja z zdravili ter tesnega sodelovanja med zdravniki in bolniki. Za vsakega bolnika moramo posebej določiti najprimernejši način zdravljenja z zdravili in v primeru, če je to neuspešno, načrtovati operacijo po intenzivnem predhodnem lokalnem zdravljenju in zdravljenju astme v sodelovanju s pulmologom.
Deskriptorji		ASPIRIN NASAL POLYPS POSTOPERATIVE COMPLICATIONS PHYSICIAN-PATIENT RELATIONS HEALTH EDUCATION TREATMENT OUTCOME