Avtor/Urednik     Turel, Iztok; Šonc, Andrej; Zupančič, Marija; Sepčić, Kristina; Turk, Tom
Naslov     Biological activity of some magnesium(II) complexes of quinolones
Tip     članek
Vir     Met-Based Drug
Vol. in št.     Letnik 7, št. 2
Leto izdaje     2000
Obseg     str. 101-4
Jezik     eng
Abstrakt     A new magnesium complex of quinolone antibacterial agent was prepared. This new complex as well as a previously isolated complex of magnesium with ciprofloxacin were tested against various Gram positive and Gram negative microorganisms. Antimicrobial activities were evaluated using the agar diffusion test. The results have shown that all magnesium complexes are significantly less active than the parent quinolone drugs. It was also found that the activity of quinolones is reduced when the solutions of quinolones are titrated with magnesium ions.
Deskriptorji     QUINOLONES
MAGNESIUM
MICROBIAL SENSITIVITY TESTS
CIPROFLOXACIN
COLONY COUNT, MICROBIAL