Avtor/Urednik     Pawlik-Juzkow, H; Knapowski, J
Naslov     Index of impediment of peritoneum and collagen content in its submesothelial tissue
Tip     članek
Vir     In: Lindič J, Kaplan-Pavlovčič S, editors. Zbornik prispevkov 1. slovenski nefrološki kongres z mednarodno udeležbo; 1996 okt 23-26; Portorož. Ljubljana: Klinični center, Nefrološka klinika,
Leto izdaje     2000
Obseg     str. 244-7
Jezik     eng
Abstrakt     The experiments were carried out on isolated fragments of rabbit mesentery, anterior abdominal wall, and diaphragm. The membranes were mounted between two semichambers filled with Hanks solution; the volume on both sides of the membrane was strictly controlled by photogauges coupled with microdosimeters. Transmembrane volume flow (Jv; nL / sec (cm2) induced by hydrostatic pressure gradient ((P; atm) was measured using an electronic device connected with the photogauges, and joined with a computer which monitored the values throughout the experiment. Hydraulic conductivity (Lp; in cm / sec (atm) and index of impediment (Zp; in sec (atm / cm) were calculated from the monitored values. Collagen content in mg per 10 mg of dry tissue of these tissues was estimated using biochemical Woessnerzs method. Both these values referring to these particular parts of peritoneum were confronted. The results were as follows (Zp and collagen content, respectively; mean (SEM): mesentery 2.6 +- 0.25 (n = 12), 1.14 +- 0.12 (n = 15), anterior abdominal wall 15.9 +- 1.5 (n = 73), 3.2 +- 0.46 (n = 15), diaphragm 111.1 +- 12.2 (n = 34), 1.83 +- 0.24 (n = 15). Differences between these groups, and statistical correlation between the values proved to be significant. The obtained results seem to show that various parts of peritoneum may function qualitatively different during dialysis, however, any conclusion concerning clinical aspects of the dialysis should be drawn with all proper reserves.
Deskriptorji     PERITONEAL DIALYSIS
PERITONEUM
HYDROSTATIC PRESSURE
COLLAGEN
RABBITS
MESENTERY
DIAPHRAGM