Avtor/Urednik		Mesar, Tomaž; Selič, L; Anžič, B; Prevec, T; Vilar, M; Grahek, R; Kocjan, D; Čopar, A; Šolmajer, T
Naslov		Vpliv strukturnih elementov v molekuli na inhibicijsko delovanje tricikličnih inhibitorjev beta-laktamaze
Tip		članek
Vir		In: Glavič P, Brodnjak-Vončina D, editors. Zbornik referatov s posvetovanja Slovenski kemijski dnevi 2000: 1. in 2. del; 2000 sep 28-29; Maribor. Maribor: FKKT,
Leto izdaje		2000
Obseg		str. 102-7
Jezik		slo
Abstrakt		Some new tricyclic analogs of beta-lactams with potential action on beta-lactamases were synthesised. Our scope was to find out which functional groups are needed for inhibition. Reaction mechanism of compound Lek-157 in nonenzymatic conditions was investigated and confirmed with beta-lactamase type A.
Deskriptorji		BETA-LACTAMASES ANTIBIOTICS, LACTAM BETA-LACTAM RESISTANCE DRUG INDUSTRY CHEMISTRY, PHARMACEUTICAL