Avtor/Urednik     Furlan, Borut; Kocjan, Darko; Grahek, Rok; Uštar, Matjaž; Žmitek, Janko
Naslov     Raziskava profila in izvora nečistoč v amlodipinu benzensulfonatu
Tip     članek
Vir     In: Glavič P, Brodnjak-Vončina D, editors. Zbornik referatov s posvetovanja Slovenski kemijski dnevi 2000: 1. in 2. del; 2000 sep 28-29; Maribor. Maribor: FKKT,
Leto izdaje     2000
Obseg     str. 119-24
Jezik     slo
Abstrakt     Impurity profile of the amlodipine benzenesulfonate prepared from trityl-amlodipine was investigated. Knowing the identity and origin of the impurities the technology for the synthesis was optimized affording the active compound of high purity. For this purpose influences on the trans-esterification of amlodipine benzenesulfonate was particularly investigated.
Deskriptorji     AMLODIPINE
BENZENESULFONATES
DRUG CONTAMINATION
DRUG INDUSTRY
CHEMISTRY, PHARMACEUTICAL