Avtor/Urednik		Erman, Andreja; Jezernik, Kristijan
Naslov		Mouse urothelial cells in early postnatal development - proliferation and apical plasma membrane specialization
Tip		članek
Vir		Pflugers Arch
Vol. in št.		Letnik 440, št. 5 Suppl
Leto izdaje		2000
Obseg		str. R183-4
Jezik		eng
Abstrakt		The purpose of this work was to investigate proliferation and differentiation of the mouse urothelial cells from the day of birth until the 5th postnatal day. The expression of proliferating cell nuclear antigen (PCNA) was studied immunocytochemically and the differentiation of apical plasma membrane of superficial cells was analysed by scanning microscopy. It was established that proliferation activity is very high during all five days since PCNA positive cells are seen in the superficial and in basal cell layer of the urothelium. Results of scanning microscopy show that the differentiation of superficial urothelial cells is a nonsynchronous process, which gradually progresses from the day of birth and leads into homogeneous population of terminally differentiated superficial cells on the 5th postnatal day.
Deskriptorji		UROTHELIUM CELL DIVISION CELL DIFFERENTIATION PROLIFERATING CELL NUCLEAR ANTIGEN BLADDER MICE HISTOCYTOCHEMISTRY MICROSCOPY, ELECTRON, SCANNING