| Avtor/Urednik | Košnik, Mitja; Kern, Izidor; Mušič, E | |
| Naslov | Chloroquin-induzierte arzneimitteltoxische alveolitis | |
| Prevedeni naslov | Chloroquine-induced drug-hypersensitivity | |
| Tip | članek | |
| Vir | Pneumologie | |
| Vol. in št. | Letnik 54 | |
| Leto izdaje | 2000 | |
| Obseg | str. 395-7 | |
| Jezik | ger | |
| Abstrakt | Chloroquine-Induced Drug-Hypersensitivity: This case history presents a 41-years-old man with chronic discoid erythematosus who was treated with chloroquine. After 2 weeks of treatment he developed dyspnea, purulent sputum, high fever, diffuse papular rash, and diffuse peripheral homogeneous infiltrates on chest x-ray. Rapid recovery occurred after discontinning chloroquine. Subsequent peroral provocation with chloroquine caused symptoms suggestive of hypersensitivity pneumonitis. Analysis of bronchoalveolar lavage fluid showed eosinophilia and a reduced CD4/CD8 ratio. Although treatment with chloroquine is often complicated by side effects, in a literature search we could not find any report on acute pneumonitis. | |
| Deskriptorji | LUPUS ERYTHEMATOSUS, DISCOID DRUG HYPERSENSITIVITY CHLOROQUINE ALVEOLITIS, EXTRINSIC ALLERGIC ADULT |