Avtor/Urednik		Pavčnik, Dušan; Uchida, Barry T; Timmermans, Hans; Petersen, Bryan; Loriaux, Marc; Yamakado, Koichiro; Voda, Jan; Yin, Qiang; Keller, Frederick S; Roesch, Josef
Naslov		Bifurcated drum occluder endograft for treatment of abdominal aortic aneurysm: an experimental study in dogs
Tip		članek
Vir		J Vasc Interv Radiol
Vol. in št.		Letnik 12
Leto izdaje		2001
Obseg		str. 359-64
Jezik		eng
Abstrakt		Purpose: To evaluate a new, low profile, home-made, bifurcated drum occluder endograft (BDOEG), designed for percutaneous, transcatheter treatment of abdominal aortic aneurysm (AAA). Materials and methods: AAA was created in 10 dogs with over-dilated Palmaz stents. To-prevent back filling, the lumbar arteries inferior mesenteric-artery, and common internal iliac arteries were embolized. The BDOEG was constructed of a drum occluder device and two PTFE endografts. The drum device consisted of a modified Z stent with Dacron stretched across and held within the ends of the stent, each with two 8 x 6-mm slits through which PTFE endografts were delivered. The PTFE endografts were 8 mm in diameter and 9.5 cm in length. Preloaded, the BDOEG was delivered through a 10-F sheath from both femoral arteries in a three-step procedure. All 10 animals were treated with BDOEG. Aortography was performed immediately, 6 weeks, and 12 weeks after stent-graft placement. Five animals were killed at 6 weeks and five were killed at 3 months. Gross and histologic evaluation was performed. Results: The infrarenal aortic diameters and both external iliac arteries ranged from 8.0 mm to 10.3 mm (mean, 9.4 mm +- 0.6) and from 5.2 mm to 6.8 mm (mean, 5.8 mm +- 0.5), respectively. Creation of the AAA was successful in all 10 dogs. AAA diameters ranged from 13.7 mm to 15.9 mm (mean, 14.9 mm +- 0.7). Complete exclusion of the AAA was achieved immediately after BDOEG placement and aneurysms remained excluded without perigraft leak to the time of killing in all 10 animals. There was a high incidence of aortoiliac limb occlusion. Occlusion of 12 aortoiliac limbs (60%) caused by intimal hyperplasia at the distal end of the endografts in iliac arteries developed in nine animals (90%). In six animals (60%), one limb occluded and, in three animals (30%), there was occlusion of both limbs. (Abstract truncated at 2000 characters)
Deskriptorji		AORTIC ANEURYSM, ABDOMINAL STENTS AORTOGRAPHY DOGS GRAFT OCCLUSION, VASCULAR BLOOD VESSEL PROSTHESIS DISEASE MODELS, ANIMAL